GWAS Summary Statistics Download | Brain Imaging Genetics Knowledge Portal

Datasets available

Largest sample

450K

Latest version

Jan 2026

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When reporting results of research that utilizes these data we request that you cite the original publication. For more summary statistic downloads from BIG-S2, click here

TBSS GWAS Summary Statistics

Sample size: n=50,000
Version: Jan 1, 2026

Download Summary Statistics:

Data available at Zenodo
data: https://zenodo.org/records/18120386

Description: TBSS summary statistics
Citation: citation to be updated

PSC GWAS Summary Statistics

Sample size: n=41,000
Version: Jan 1, 2026

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Data available at Zenodo
LDRs/coords/fpca/bases: https://zenodo.org/records/18120954

Sumstat/Snpinfo files below:
Phase 1-5 part 1: https://zenodo.org/records/18102578
Phase 1-5 part 2: https://zenodo.org/records/18102569
Phase 1-5 part 3: https://zenodo.org/records/18102570c
Phase 1-5 part 4: https://zenodo.org/records/18102556
Phase 1-5 part 5: https://zenodo.org/records/18102572
Phase 1-5 part 6: https://zenodo.org/records/18102560
Phase 1-5 part 7: https://zenodo.org/records/18102571
Phase 1-5 part 8: https://zenodo.org/records/18102567
Phase 1-5 part 9: https://zenodo.org/records/18102574
Phase 1-5 part 10: https://zenodo.org/records/18102576
Phase 1-5 part 11: https://zenodo.org/records/18102593
Phase 1-5 part 12: https://zenodo.org/records/18102587
Phase 1-5 part 13: https://zenodo.org/records/18102565
Phase 1-5 part 14: https://zenodo.org/records/18102568

Phase 6 part 1: https://zenodo.org/records/18102606
Phase 6 part 2: https://zenodo.org/records/18102598
Phase 6 part 3: https://zenodo.org/records/18102605
Phase 6 part 4: https://zenodo.org/records/18102601
Phase 6 part 5: https://zenodo.org/records/18102607
Phase 6 part 6: https://zenodo.org/records/18102602
Phase 6 part 7: https://zenodo.org/records/18102611
Phase 6 part 8: https://zenodo.org/records/18102604
Phase 6 part 9: https://zenodo.org/records/18102609
Phase 6 part 10: https://zenodo.org/records/18102613
Phase 6 part 11: https://zenodo.org/records/18102564
Phase 6 part 12: https://zenodo.org/records/18102555
Phase 6 part 13: https://zenodo.org/records/18102592
Phase 6 part 14: https://zenodo.org/records/18102590

Description: readme
Citation: citation to be updated

Disease GWAS Summary Statistics

Sample size: n=450,000
Version: Jan 1, 2026

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Data available at Zenodo
data: https://zenodo.org/records/17968936

Description: Trait list inside download
Citation: citation to be uploaded

ANTs GWAS Summary Statistics

Sample size: n=50,000
Version: Jan 1, 2026

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Data available at Zenodo
Left and Right Hemisphere: https://zenodo.org/records/17933585
Other: https://zenodo.org/records/17933613

Description: ANTS GWAS summary statistics
Citation: citation to be updated

fMRI ICA GWAS summary statistics on

Sample size: n=58,588
Version: Jan 1, 2026

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Data available at Zenodo
Full Correlation V1-100: https://zenodo.org/records/17903869
Full Correlation V101-200: https://zenodo.org/records/17915313
Full Correlation V201-300: https://zenodo.org/records/17916505
Partial Correlation V1-100: https://zenodo.org/records/17916009
Partial Correlation V101-200: https://zenodo.org/records/17916011
Partial Correlation V201-300: https://zenodo.org/records/17916013

Description: ICA GWAS
Citation: citation to be updated

Shape GWAS summary statistics on

Sample size: n=68,813
Version: Jan 1, 2026

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Data available at Zenodo
Accu Phase1to5: https://zenodo.org/records/17186625
Accu Phase6: https://zenodo.org/records/17181130
Amyg Phase1to5: https://zenodo.org/records/17180887
Amyg Phase6: https://zenodo.org/records/17180901
Caud Phase1to5: https://zenodo.org/records/17180943
Caud Phase6: https://zenodo.org/records/17180963
Hipp Phase1to5: https://zenodo.org/records/17180967
Hipp Phase6: https://zenodo.org/records/17180972
Pall Phase1to5: https://zenodo.org/records/17969256
Pall Phase6: https://zenodo.org/records/17186671
Puta Phase1to5: https://zenodo.org/records/17180978
Puta Phase6: https://zenodo.org/records/17180990
Thal Phase1to5: https://zenodo.org/records/17969273
Thal Phase6: https://zenodo.org/records/17180689
Vent Phase1to5: https://zenodo.org/records/17969268
Vent Phase6: https://zenodo.org/records/17186702

Description: readme
Citation: citation to be added

XWAS summary statistics for Multi-Organ Data

Sample size: n between 2058~46662 depending on the phenotype
Version: Jan 1, 2026

Download Summary Statistics:

Data available at Zenodo
https://zenodo.org/records/17082113

Description: Trait List and info inside the download
Citation: citation to be updated

GWAS summary statistics for 200 resting-state functional MRI (rs-fMRI) traits

Sample size: n=34,691
Version: July 15, 2020

Download Summary Statistics:

Data available at Zenodo
//doi.org/10.5281/zenodo.5775047

Description: readme
Citation: Zhao et al (2020) Common variants contribute to intrinsic human brain functional networks. Nature Genetics. https://doi.org/10.1038/s41588-022-01039-6

GWAS summary statistics for 635 tract-specific diffusion tensor imaging (DTI) parameters

Sample size: n=33,292
Version: July 15, 2020

Download Summary Statistics:

wget --no-check-certificate --content-disposition https://github.com/stat-yyang/sumstats/blob/master/110_mean.list 
wget --no-check-certificate --content-disposition https://github.com/stat-yyang/sumstats/blob/master/105_mopcs.list 
wget --no-check-certificate --content-disposition https://github.com/stat-yyang/sumstats/blob/master/105_rdpcs.list 
wget --no-check-certificate --content-disposition https://github.com/stat-yyang/sumstats/blob/master/105_adpcs.list 
wget --no-check-certificate --content-disposition https://github.com/stat-yyang/sumstats/blob/master/105_mdpcs.list 
wget --no-check-certificate --content-disposition https://github.com/stat-yyang/sumstats/blob/master/105_fapcss.list
wget -i 110_mean.list
wget -i 105_mopcs.list
wget -i 105_rdpcs.list
wget -i 105_adpcs.list
wget -i 105_mdpcs.list
wget -i 105_fapcs.list

Data available at Zenodo
mean: https://doi.org/10.5281/zenodo.4549730
MO PC: https://doi.org/10.5281/zenodo.4553513
RD PC: https://doi.org/10.5281/zenodo.4553510
AD PC: https://doi.org/10.5281/zenodo.4553514
MD PC:  https://doi.org/10.5281/zenodo.4549693
FA PC: https://doi.org/10.5281/zenodo.4549725

Description: readme
Citation: Zhao et al (2021) Common genetic variation influencing human white matter microstructure. Science. https://doi.org/10.1126/science.abf3736.

GWAS Summary Statistics for 101 Brain Regional Volumes

Sample size: n=19,629
Version: May 24, 2019
Download links: GWAS Summary Statistics readme (UK Biobank) readme (meta-analysis)
Citation: Zhao et al. (2019) Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health` Traits. Nature Genetics. https://www.nature.com/articles/s41588-019-0516-6

GWAS summary statistics for 110 brain regional diffusion tensor imaging (DTI) parameters

Sample size: n=17,706
Version: March 11, 2019
Download links: GWAS Summary Statistics readme
Citation: Zhao et al. (2019) Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health` traits (n=17,706). Molecular Psychiatry. https://www.nature.com/articles/s41380-019-0569-z

Summary statistics of the sex chromosomes for 2,822 brain imaging traits

Sample size: n=34,000
Version: Sept. 1, 2023
Download Summary Statistics: GWAS Summary Statistics readme
Citation: Jiang et al. (2023) The pivotal role of the X-chromosome in the genetic architecture of the human brain. medRxiv. https://doi.org/10.1101/2023.08.30.23294848